Patients w/ a certain human leukocyte antigen genotype are more prone to development of insulin autoimmune syndrome when treated w/ thioctic acid. Sugar intolerance. Pregnancy. Should not be taken while breast-feeding. Should not be given to childn & juveniles.
May diminish effect of cisplatin. May potentiate hypoglycemic effect of insulin or oral antidiabetics. May cause chelation w/ metal compd (eg, Fe prep, Mg prep, milk products). Avoid alcohol.
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